>90%
mRNA Purity
Built for Speed, Quality, and Scale
Your mRNA journey starts with a strong foundation. From plasmid engineering to LNP formulation, every step is optimized for performance, compliance, and speed to clinic.
One Stop Solution
ProBio’s one-stop platform streamlines every stage of mRNA therapeutic development—the seamless connection between in-house plasmid production to mRNA-LNP ensures an effective project development cycle. In-house QC and analytical development minimizes tech transfer risk while accelerating timelines.
Scalable LNP Formulation Platforms
Our LNP services are built on advanced microfluidic encapsulation platforms that allow precise control over lipid ratios, flow rates, and particle formation conditions. We offer full process transfer and scale-up from R&D formulations to clinical-grade production, including DoE optimization and GMP readiness.
In-House Analytical Development
Our integrated analytical team supports every stage of your mRNA product lifecycle with comprehensive release and characterization assays. Our team has extensive experience in developing customized bioassays tailored to your specific therapeutic needs.
Regulatory Alignment at Every Phase
From early research through IND submission and commercial launch, our mRNA workflows are designed to meet global regulatory expectations. We offer phase-appropriate QA/QC packages, batch documentation, and analytical method validation aligned with FDA and EMA guidelines.
From Plasmid to mRNA
Streamlined and Connected Workflows
ProBio offers a fully integrated mRNA CDMO platform that connects plasmid production, IVT-mRNA synthesis, and LNP encapsulation into one seamless process. Whether you're in early research or preparing for clinical submission, our process is designed to be scalable, reproducible, and compliant across all phases.
With in-house analytical development and phase-appropriate quality oversight, we help reduce handoffs and accelerate your time to clinic—all within a single, vertically integrated CDMO
Linearization and Cell-Free Solutions for IVT Templates
ProBio has three distinct linearization platforms to fully fit your development needs including an advanced cell-free solution for enzymatically linearized DNA templates for high yield and fast turnaround.
IVT Template Solutions for Optimal mRNA Production
- Linearized DNA formats tailored to specific development needs.
- Flexible manufacturing pathways to align with project speed, scale, and regulatory phase.
- Advanced solutions for maximum yield, and minimal impurities.
Your Trusted mRNA CDMO
ProBio delivers consistent, high-quality, regulatory-ready solutions at every phase—from R&D to commercial. Our proven track record supports global programs with speed, scalability, and precision.
>98%
IVT Template Purity
6 Month
IND Solution from Plasmid to mRNA
>50
Global mRNA Projects
>10
mRNA IND approvals (NMPA, FDA, PMDA, MFDS, Ministry of Health)
Up to 99.7%
mRNA-LNP encapsulation efficiency
Plasmid Solutions for High-Quality IVT Templates
Our industry-leading plasmid platform delivers consistent, high-purity products designed to meet the rigorous demands of IVT template generation. With >95% supercoil plasmid product and optimized processes from research-grade through GMP, we provide exceptional quality, scalability, and compliance at every phase.
Plasmids That Power mRNA Excellence
- Unmatched purity and supercoiled content for efficient enzymatic linearization
- Seamless scalability across preclinical, IND, and commercial programs
